Cups of coffee on a brown background.
Caffeine should be avoided by patients with lupus as it can increase stress and cause issues sleeping.

What is Lupus?

Lupus is a chronic autoimmune disease that affects different parts of the body such as a person's skin, joints and kidneys. Managing lupus involves more than just medication; lifestyle choices, such as diet, play a crucial role in controlling symptoms and preventing flare-ups. In this article, we will discuss the drinks that people with lupus should avoid and explain why they are harmful. We will also explore different treatment options available for lupus, including the medication Lupkynis (voclosporin).

Drinks to Avoid with Lupus

Managing lupus effectively requires paying close attention to what you consume, especially in terms of beverages. Certain drinks can make symptoms worse or interact negatively with medications. Here's what to avoid.

  1. Alcoholic beverages: Alcohol can interfere with the effectiveness of medications commonly prescribed for lupus, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids. Additionally, alcohol can increase the risk of liver damage, particularly in individuals taking immunosuppressive drugs. Alcohol can also contribute to dehydration, which may exacerbate lupus symptoms such as fatigue and joint pain.
  2. Sugary drinks: Sugary drinks, including sodas and sweetened fruit juices, can lead to weight gain and increase the risk of developing other health issues, such as diabetes and cardiovascular disease. For individuals with lupus, maintaining a healthy weight is crucial because obesity can worsen inflammation and place additional strain on the joints. Excessive sugar intake can also contribute to increased inflammation, making lupus symptoms more difficult to manage.
  3. Caffeinated beverages: While moderate caffeine consumption is generally safe, excessive intake of caffeinated beverages, such as coffee, energy drinks and certain teas, can lead to increased anxiety, sleep disturbances and heart palpitations. For individuals with lupus, managing stress and getting adequate rest are essential for controlling symptoms. High caffeine intake can interfere with these goals and may also interact with certain lupus medications, such as corticosteroids, leading to elevated blood pressure and other complications.
  4. Artificially sweetened drinks: Drinks containing artificial sweeteners, such as diet sodas, are often marketed as healthier alternatives to sugary beverages. However, some studies suggest that artificial sweeteners may contribute to increased inflammation and disrupt the balance of gut bacteria, which can negatively impact the immune system. For individuals with lupus, maintaining a balanced immune response is critical, and consuming artificial sweeteners could potentially exacerbate symptoms.
  5. High-sodium drinks: High-sodium drinks, including certain types of vegetable juices and sports drinks, can contribute to increased blood pressure and fluid retention. For individuals with lupus, particularly those with lupus nephritis (a condition that affects the kidneys), it is essential to manage sodium intake to prevent worsening kidney function and reduce the risk of complications such as hypertension and edema.
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Treatment Options for Lupus

While lifestyle changes, including dietary adjustments, are important for managing lupus, medications are often necessary to control symptoms, reduce inflammation and prevent organ damage. The treatment plan for lupus is highly individualized and may include a combination of medications and therapies.

  • Lupkynis (voclosporin): This is a newer medication specifically approved for the treatment of lupus nephritis, a serious complication of lupus that affects the kidneys. Lupkynis is an immunosuppressant that helps reduce inflammation in the kidneys and prevent further damage. It is often used in combination with other treatments, such as corticosteroids and mycophenolate mofetil, to achieve better control of lupus nephritis.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs, such as ibuprofen and naproxen, are commonly used to relieve pain, reduce inflammation, and manage fever in individuals with lupus. They are particularly helpful for treating joint pain and stiffness.
  • Corticosteroids: Corticosteroids, such as prednisone, are powerful anti-inflammatory drugs that can help control lupus flare-ups. They are often prescribed in higher doses during active disease phases and tapered down as symptoms improve. However, long-term use of corticosteroids can lead to side effects, including weight gain, osteoporosis and an increased risk of infections.
  • Antimalarial drugs: Medications like hydroxychloroquine (Plaquenil) are commonly used to manage lupus symptoms, particularly skin rashes, joint pain and fatigue. Antimalarials can also help prevent lupus flare-ups and reduce the risk of long-term organ damage. They are generally well-tolerated and have been a mainstay of lupus treatment for many years.
  • Immunosuppressants: Immunosuppressive drugs, such as azathioprine, mycophenolate mofetil and methotrexate, are used to suppress the immune system's overactivity in lupus. These medications are often prescribed for individuals with more severe disease or when other treatments are not effective. Immunosuppressants can help prevent the immune system from attacking healthy tissues, thereby reducing inflammation and organ damage.
  • Biologics: Biologic drugs, such as belimumab (Benlysta), target specific proteins in the immune system that contribute to lupus. Belimumab is often used in combination with other medications to treat lupus in individuals who have not responded well to traditional therapies. Biologics represent a more targeted approach to treatment, potentially offering benefits with fewer side effects.