A woman sitting on her couch with a blanket, blowing her nose.
Chronic fatigue and fevers are signs of ITP, which can affect a person's immune system.

How to Recognize Common Signs

Immune thrombocytopenic purpura (ITP) is a condition in which the immune system mistakenly attacks and destroys platelets, which are essential for blood clotting. To help, there's Doptelet, which helps reduce bleeding and boosts immune functionality.

Common Symptoms of ITP that Affect Immunity

ITP can be difficult to catch because there are not always noticeable symptoms. However, if symptoms do flare up, some of the most commons ones include:

  1. Bruising easily.
  2. Bleeding into the skin that looks like tiny reddish-purple spots that look like a rash. The spots mostly show up on the lower legs.
  3. Bleeding from the gums or nose.
  4. Blood in urine or stools.
  5. Excessively heavy menstrual flow.

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Symptoms of ITP

Frequent Infections

The immune system may not function at its full capacity, making the body more susceptible to viruses, bacteria and other pathogens. This makes frequent infections more likely. Individuals with ITP may experience recurrent respiratory infections, urinary tract infections or skin infections more often than usual.

Prolonged Recovery from Illnesses

People with ITP may notice that it takes them longer to recover from common illnesses like colds or the flu. The immune system struggles to mount an adequate response, prolonging the duration of these ailments and making it more difficult for the body to fight off infections efficiently.

Delayed Wound Healing

In addition to a prolonged recovery from illnesses, people with ITP may also experience a delay in wound healing. In patients with ITP, the reduced number of platelets can mean slower clot formation, which in turn delays the healing of cuts, bruises or other injuries.

Chronic Fatigue

Chronic fatigue is another sign that the immune system may be compromised. Chronic fatigue goes beyond normal tiredness and is understood as a debilitating fatigue that doesn’t go away even after proper rest.

Recurring Fevers

Fevers are the body’s natural response to infection. In those with ITP, the immune system may be in overdrive, frequently triggering fevers in response to minor infections or internal imbalances.

Treatment Options to Boost Immunity

Managing ITP involves treating both the symptoms of low platelet counts and the weakened immune system that results from the condition. Treatment options can vary depending on the severity of the ITP.

Dopelet

Doplet is a thrombopoietin receptor agonist that helps increase platelet production in the bone marrow. By raising the platelet count, Doptelet can reduce the risk of bleeding and improve overall immune function.

Immunoglobulin Therapy (IVIG)

Intravenous immunoglobulin (IVIG) can temporarily increase platelet counts by providing antibodies that help block the immune system's destruction of platelets. This therapy is often used in cases where rapid platelet elevation is necessary, such as during surgery or following a severe bleeding episode.

Corticosteroids

Corticosteroids, such as prednisone, are commonly prescribed to suppress the immune system’s attack on platelets. They do come with some risks, however. While they can help increase platelet counts in the short term, long-term use may weaken the immune system further and increase the risk of infections.

Splenectomy

In some cases, surgical removal of the spleen may be recommended. Removing the spleen can help to increase platelet counts. However, this procedure comes with risks. It may further weaken immunity, as the spleen plays a role in fighting infections.

Lifestyle Changes

Lifestyle modifications can make a difference in the lives of people with ITP. Introducing a balanced diet rich in vitamins and minerals, regular exercise and adequate sleep can help support overall immune function. You can also introduce supplements like vitamin C, vitamin D and zinc into your diet to boost immunity and reduce the risk of infections.